Exploring the polymorphism of sofosbuvir via mechanochemistry: effect of milling jar geometry and material

Argyro Chatziadi; Eliška Skořepová; Martin Kohout; Luděk Ridvan; Miroslav Soos

doi:10.1039/d1ce01561c

journal article Jan 01, 2022

Exploring the polymorphism of sofosbuvir via mechanochemistry: effect of milling jar geometry and material

Argyro Chatziadi

Eliška Skořepová

Martin Kohout Luděk Ridvan Miroslav Soos

CrystEngComm Vol. 24 No. 11 pp. 2107-2117 · Royal Society of Chemistry (RSC)

View at Publisher Save 10.1039/d1ce01561c

Abstract

In this work, the influence of polypropylene jar properties on the polymorphic transformations of sofosbuvir during milling experiments is investigated.

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Metrics

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Citations

39

References

Details

Published: Jan 01, 2022
Vol/Issue: 24(11)
Pages: 2107-2117
License: View

Authors

A

Argyro Chatziadi

Department of Chemical Engineering, University of Chemistry and Technology Prague, Technicka 5, Prague 6, Czech Republic

E

Eliška Skořepová

Department of Chemical Engineering, University of Chemistry and Technology Prague, Technicka 5, Prague 6, Czech Republic; Institute of Physics of the Czech Academy of Sciences, Na Slovance 2, 182 21 Praha 8, Czech Republic

M

Martin Kohout

Department of Chemical Engineering, University of Chemistry and Technology Prague, Technicka 5, Prague 6, Czech Republic

L

Luděk Ridvan

Zentiva, k.s, U Kabelovny 130, 10237, Prague 10, Czech Republic

M

Miroslav Soos

Department of Chemical Engineering, University of Chemistry and Technology Prague, Technicka 5, Prague 6, Czech Republic

Cite This Article

Argyro Chatziadi, Eliška Skořepová, Martin Kohout, et al. (2022). Exploring the polymorphism of sofosbuvir via mechanochemistry: effect of milling jar geometry and material. CrystEngComm, 24(11), 2107-2117. https://doi.org/10.1039/d1ce01561c

Exploring the polymorphism of sofosbuvir via mechanochemistry: effect of milling jar geometry and material

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