Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

Joseph L. Howard; Qun Cao; Duncan L. Browne

doi:10.1039/c7sc05371a

journal article Open Access Jan 01, 2018

Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

Joseph L. Howard Qun Cao Duncan L. Browne

Chemical Science Vol. 9 No. 12 pp. 3080-3094 · Royal Society of Chemistry (RSC)

View at Publisher Save 10.1039/c7sc05371a

Abstract

Mechanochemistry is becoming more widespread as a technique for molecular synthesis with new mechanochemical reactions being discovered at increasing frequency. This perspective explores what more it can offer, aside from the clear benefit of reduced solvent consumption.

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References

124

[1]

Do Synlett (2017) 10.1055/s-0036-1590854

[2]

Tan Eur. J. Org. Chem. (2018) 10.1002/ejoc.201700961

[3]

Do ACS Cent. Sci. (2017) 10.1021/acscentsci.6b00277

[4]

Hernandez J. Org. Chem. (2017) 10.1021/acs.joc.6b02887

[5]

IUPAC Compendium of Chemical Terminology , ed. M. Nič , J. Jirát , B. Košata , A. Jenkins and A. McNaught , IUPAC , 2009

[6]

P. Baláž , Mechanochemistry in Nanoscience and Minerals Engineering , Springer-Verlag , Berlin, Heidelberg , 2008

[7]

Hsu Tribol. Lett. (2002) 10.1023/a:1020112901674

[8]

Galembeck RSC Adv. (2014) 10.1039/c4ra09604e

[9]

Hoffmann Acc. Chem. Res. (1968) 10.1021/ar50001a003

[10]

Woodward J. Am. Chem. Soc. (1965) 10.1021/ja01080a054

[11]

Wollenhaupt ChemPhysChem (2015) 10.1002/cphc.201500054

[12]

Hickenboth Nature (2007) 10.1038/nature05681

[13]

Stevenson J. Am. Chem. Soc. (2017) 10.1021/jacs.7b08895

[14]

Wang Chem. Soc. Rev. (2013) 10.1039/c3cs35526h

[15]

James Chem. Soc. Rev. (2012) 10.1039/c1cs15171a

[16]

D. Margetić and V.Štrukil , Mechanochemical Organic Synthesis , Elsevier , Oxford , 2016

[17]

Boldyreva Chem. Soc. Rev. (2013) 10.1039/c3cs60052a

[18]

Stolle Chem. Soc. Rev. (2011) 10.1039/c0cs00195c

[19]

A. Stolle and B.Ranu , Ball Milling Towards Green Synthesis: Applications, Projects, Challenges , Royal Society of Chemistry , Cambridge , 2014 10.1039/9781782621980

[20]

Takacs J. Therm. Anal. Calorim. (2007) 10.1007/s10973-007-8479-8

[21]

Choi Met. Mater. Int. (2007) 10.1007/bf03027893

[22]

Mankosa Powder Technol. (1989) 10.1016/0032-5910(89)80084-1

[23]

Noorduin J. Am. Chem. Soc. (2008) 10.1021/ja7106349

[24]

http://new.outotec.com/products/grinding/higmill-high-intensity-grinding-mill/ , accessed March 2017

[25]

Stolle Faraday Discuss. (2014) 10.1039/c3fd00144j

[26]

Crawford Chem. Sci. (2015) 10.1039/c4sc03217a

[27]

Crawford Green Chem. (2017) 10.1039/c6gc03413f

[28]

Michalchuk Faraday Discuss. (2014) 10.1039/c3fd00150d

[29]

Kumar Rev. Sci. Instrum. (2015) 10.1063/1.4929325

[30]

Schneider Green Chem. (2009) 10.1039/b915744c

[31]

Schmidt Chem.–Eur. J. (2011) 10.1002/chem.201100604

[32]

Thorwirth Chem.–Eur. J. (2010) 10.1002/chem.201001702

[33]

Trotzki Green Chem. (2008) 10.1039/b801661e

[34]

Hutchings Angew. Chem., Int. Ed. (2017) 10.1002/anie.201706723

[35]

Do J. Am. Chem. Soc. (2015) 10.1021/jacs.5b00151

[36]

Li Lubricants (2014) 10.3390/lubricants2010021

[37]

Friščić CrystEngComm (2009) 10.1039/b815174a

[38]

Shan Chem. Commun. (2002) 10.1039/b207369m

[39]

Hasa Cryst. Growth Des. (2016) 10.1021/acs.cgd.6b00682

[40]

Egbert Catal. Sci. Technol. (2013) 10.1039/c2cy20816d

[41]

Lin Chem. Rev. (2009) 10.1021/cr8005153

[42]

Lazreg Coord. Chem. Rev. (2015) 10.1016/j.ccr.2014.12.019

[43]

Díez-González Synlett (2007) 10.1055/s-2007-985577

[44]

Liu Dalton Trans. (2015) 10.1039/c4dt02986k

[45]

Barsoum J. Org. Chem. (2015) 10.1021/acs.joc.5b01536

[46]

Lake Chem. Commun. (2012) 10.1039/c2cc30862b

[47]

Beillard Chem. Sci. (2017) 10.1039/c6sc03182j

[48]

Lyons Chem. Rev. (2010) 10.1021/cr900184e

[49]

Davies Chem. Soc. Rev. (2011) 10.1039/c1cs90010b

[50]

Hernández Chem.–Eur. J. (2017)

Showing 50 of 124 references

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Metrics

888

Citations

124

References

Details

Published: Jan 01, 2018
Vol/Issue: 9(12)
Pages: 3080-3094
License: View

Authors

J

Joseph L. Howard

School of Chemistry; Cardiff University; Cardiff; UK

Q

Qun Cao

School of Chemistry; Cardiff University; Cardiff; UK

D

Duncan L. Browne

School of Chemistry; Cardiff University; Cardiff; UK

Funding

Engineering and Physical Sciences Research Council Award: EP/P002951/1

Cardiff University

Cite This Article

Joseph L. Howard, Qun Cao, Duncan L. Browne (2018). Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?. Chemical Science, 9(12), 3080-3094. https://doi.org/10.1039/c7sc05371a

Mechanochemistry as an emerging tool for molecular synthesis: what can it offer?

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