Functions of ABC transporters in plants

Tobias Kretzschmar; Bo Burla; Youngsook Lee; Enrico Martinoia; Réka Nagy

doi:10.1042/bse0500145

journal article Sep 07, 2011

Functions of ABC transporters in plants

Tobias Kretzschmar

Bo Burla Youngsook Lee

Enrico Martinoia

Réka Nagy

Essays in Biochemistry Vol. 50 pp. 145-160 · Portland Press Ltd.

View at Publisher Save 10.1042/bse0500145

Abstract

ABC (ATP-binding cassette) proteins are ubiquitously found in prokaryotes and eukaryotes and generally serve as membrane-intrinsic primary active pumps. In higher plants, ABC proteins constitute a large family, grouped phylogenetically into eight clusters, subfamilies ABCA–ABCI (ABCH is not found in plants). ABC transporters shuttle substrates as diverse as lipids, phytohormones, carboxylates, heavy metals, chlorophyll catabolites and xenobiotic conjugates across a variety of biological membranes. To date, the largest proportions of characterized members have been localized to the plasma membrane and the tonoplast, with dominant implications in cellular secretion and vacuolar sequestration, but they are also found in mitochondrial, plastidal and peroxisomal membranes. Originally identified as tonoplast-intrinsic proteins that shuttle xenobiotic conjugates from the cytosol into the vacuole, thus being an integral part of the detoxification machinery, ABC transporters are now recognized to participate in a multitude of physiological processes that allow the plant to adapt to changing environments and cope with biotic and abiotic stresses.

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Citations

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References

Details

Published: Sep 07, 2011
Vol/Issue: 50
Pages: 145-160

Authors

T

Tobias Kretzschmar

Institute of Plant Biology, University of Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland

B

Bo Burla

Institute of Plant Biology, University of Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland; POSTECH-UZH Global Research Laboratory, Division of Molecular Life Sciences, POSTECH University of Science and Technology, Pohang, 790-784, South Korea

Y

Youngsook Lee

POSTECH-UZH Global Research Laboratory, Division of Molecular Life Sciences, POSTECH University of Science and Technology, Pohang, 790-784, South Korea

E

Enrico Martinoia

Institute of Plant Biology, University of Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland; POSTECH-UZH Global Research Laboratory, Division of Molecular Life Sciences, POSTECH University of Science and Technology, Pohang, 790-784, South Korea

R

Réka Nagy

Institute of Plant Biology, University of Zurich, Zollikerstrasse 107, 8008 Zurich, Switzerland

Cite This Article

Tobias Kretzschmar, Bo Burla, Youngsook Lee, et al. (2011). Functions of ABC transporters in plants. Essays in Biochemistry, 50, 145-160. https://doi.org/10.1042/bse0500145

Functions of ABC transporters in plants

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