journal article Open Access Nov 09, 2021

A Review of the Effects of Collagen Treatment in Clinical Studies

Polymers Vol. 13 No. 22 pp. 3868 · MDPI AG
View at Publisher Save 10.3390/polym13223868
Abstract
Collagen, an abundant extracellular matrix protein, has been found to have a lot of pharmaceuticals, medicine, food, and cosmetics applications. Increased knowledge of collagen sources, extraction techniques, structure, and properties in the last decades has helped develop more collagen-based products and tissue engineering biomaterials. Collagen products have been playing an important role in benefiting the health of the human body, especially for aging people. In this paper, the effects of collagen treatment in different clinical studies including skin regeneration, bone defects, sarcopenia, wound healing, dental therapy, gastroesophageal reflux, osteoarthritis, and rheumatoid arthritis have been reviewed. The collagen treatments were significant in these clinical studies. In addition, the associations between these diseases were discussed. The comorbidity of these diseases might be closely related to collagen deficiency, and collagen treatment might be a good choice when a patient has more than one of these diseases, including the coronavirus disease 2019 (COVID-19). It concludes that collagen-based medication is useful in treating comorbid diseases and preventing complications.
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Citations
151
References
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Published
Nov 09, 2021
Vol/Issue
13(22)
Pages
3868
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Funding
Ministry of Science and Technology Award: 109-2118-M-009 -005 -MY2
Cite This Article
Hsiuying Wang (2021). A Review of the Effects of Collagen Treatment in Clinical Studies. Polymers, 13(22), 3868. https://doi.org/10.3390/polym13223868
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