Researcher Profile

Ligen Lin

0000-0002-6799-5327

Publications

640

Citations

Co-Authors

Active Years

Publications

Open Access Journal Article Acta Pharmaceutica Sinica B Aug 01, 2024

Small molecule α-methylene-γ-butyrolactone, an evolutionarily conserved moiety in sesquiterpene lactones, ameliorates arthritic phenotype via interference DNA binding activity of NF-κB

Kegang Linghu · Wenqing Cui · Taiqin Li · Yueting Tuo +8 more

10.1016/j.apsb.2024.04.004 29 citations

Journal Article Free Radical Biology and Medicine Jun 01, 2023

Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction

Qingwen Xiao · Bingling Zhong · Ying Hou · Miaojuan Wang +4 more

10.1016/j.freeradbiomed.2023.03.020 26 citations

Open Access Journal Article Molecular Therapy - Nucleic Acids Dec 01, 2023

Exosomal miRNA-155-5p from M1-polarized macrophages suppresses angiogenesis by targeting GDF6 to interrupt diabetic wound healing

Ruohan Lou · Jiali Chen · Fei Zhou · Tian Zhang +3 more

10.1016/j.omtn.2023.102074 35 citations

Open Access Journal Article Nature Communications Jun 07, 2021

A small molecule HIF-1α stabilizer that accelerates diabetic wound healing

Guodong Li · Chung-Nga Ko · Dan Li · Chao Yang +7 more

10.1038/s41467-021-23448-7 220 citations

Journal Article British Journal of Pharmacology Aug 20, 2020

Small molecule‐driven SIRT3‐autophagy‐mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes

Tian Zhang · Zhujun Fang · Ke‐Gang Linghu · Jingxin Liu +2 more

10.1111/bph.15215 64 citations

Open Access Journal Article Cell Death & Differentiation Jun 03, 2019

SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity

Tian Zhang · Jingxin Liu · Shengnan Shen · Qiang Tong +2 more

10.1038/s41418-019-0356-z 156 citations

Open Access Journal Article Acta Pharmaceutica Sinica B Mar 01, 2019

Small molecules for fat combustion: targeting obesity

Jingxin Liu · Ligen Lin

10.1016/j.apsb.2018.09.007 110 citations

Publication Timeline

2024

2023

2021

2020

2019

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