Researcher Profile

Mark Cushman

Publications

273

Citations

Co-Authors

Active Years

Publications

Journal Article Journal of Medicinal Chemistry Mar 26, 2015

Synthesis and Biological Evaluation of Nitrated 7-, 8-, 9-, and 10-Hydroxyindenoisoquinolines as Potential Dual Topoisomerase I (Top1)–Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors

Trung Xuan Nguyen · Monica Abdelmalak · Christophe Marchand · Keli Agama +2 more

10.1021/acs.jmedchem.5b00136 53 citations

Journal Article The Journal of Antibiotics Oct 15, 2014

Anti-biofilm activity and synergism of novel thiazole compounds with glycopeptide antibiotics against multidrug-resistant Staphylococci

Haroon Mohammad · Abdelrahman S Mayhoub · Mark Cushman · Mohamed N Seleem

10.1038/ja.2014.142 77 citations

Open Access Journal Article Structure Oct 01, 2002

Studies on the Reaction Mechanism of Riboflavin Synthase

Stefan Gerhardt · Ann-Kathrin Schott · Norman Kairies · Mark Cushman +6 more

10.1016/s0969-2126(02)00864-x 68 citations

Journal Article Journal of Medicinal Chemistry Jan 19, 2001

Correlation of Anti-HIV Activity with Anion Spacing in a Series of Cosalane Analogues with Extended Polycarboxylate Pharmacophores

Kalpathy C. Santhosh · Gitendra C. Paul · Erik De Clercq · Christophe Pannecouque +5 more

10.1021/jm000290u 19 citations

Journal Article Bioorganic & Medicinal Chemistry Jan 01, 2000

Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain

Agustin Casimiro-Garcia · Erik De Clercq · Christophe Pannecouque · Myriam Witvrouw +4 more

10.1016/s0968-0896(99)00269-2 9 citations

Journal Article Bioorganic & Medicinal Chemistry Letters Nov 01, 2000

Anti-HIV activity of a series of cosalane amino acid conjugates

Kalpathy C Santhosh · Erik De Clercq · Christophe Pannecouque · Myriam Witvrouw +4 more

10.1016/s0960-894x(00)00515-1 5 citations

Journal Article Bioorganic & Medicinal Chemistry Letters Sep 01, 2000

Identification of optimal anion spacing for anti-HIV activity in a series of cosalane tetracarboxylates

Gitendra C Paul · Erik De Clercq · Christophe Pannecouque · Myriam Witvrouw +4 more

10.1016/s0960-894x(00)00417-0 4 citations

Journal Article Journal of Medicinal Chemistry Apr 28, 1999

Extension of the Polyanionic Cosalane Pharmacophore as a Strategy for Increasing Anti-HIV Potency

Mark Cushman · Shabana Insaf · Gitendra Paul · Jeffrey A. Ruell +8 more

10.1021/jm980727m 13 citations

Journal Article Journal of Medicinal Chemistry Jan 01, 1996

Correlation of Anti-HIV Potency with Lipophilicity in a Series of Cosalane Analogs Having Normal Alkenyl and Phosphodiester Chains as Cholestane Replacements

Robert F. Keyes · W. Marek Golebiewski · Mark Cushman

10.1021/jm950666h 25 citations

Publication Timeline

2015

2014

2002

2001

2000

1999

1996

Frequent Co-Authors

Myriam Witvrouw

5×

Christophe Pannecouque

5×

5×

3×

2×

2×

2×

1×

1×

1×