Topics

No keywords indexed for this article. Browse by subject →

References
32
[1]
Burden and Cost of Gastrointestinal, Liver, and Pancreatic Diseases in the United States: Update 2018

Anne F. Peery, Seth D. Crockett, Caitlin C. Murphy et al.

Gastroenterology 2019 10.1053/j.gastro.2018.08.063
[2]
Rizvi "Emerging molecular therapeutic targets for cholangiocarcinoma" J Hepatol (2017) 10.1016/j.jhep.2017.03.026
[3]
Genomic spectra of biliary tract cancer

Hiromi Nakamura, Yasuhito Arai, Yasushi Totoki et al.

Nature Genetics 2015 10.1038/ng.3375
[4]
Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

Apinya Jusakul, Ioana Cutcutache, Chern Han Yong et al.

Cancer Discovery 2017 10.1158/2159-8290.cd-17-0368
[6]
Farshidfar "Integrative genomic analysis of cholangiocarcinoma identifies distinct IDH-mutant molecular profiles" Cell Rep (2017) 10.1016/j.celrep.2017.06.008
[7]
Dong "Spatial and temporal clonal evolution of intrahepatic cholangiocarcinoma" J Hepatol (2018) 10.1016/j.jhep.2018.02.029
[8]
Hogdall "Desmoplastic tumor microenvironment and immunotherapy in cholangiocarcinoma" Trends Cancer (2018) 10.1016/j.trecan.2018.01.007
[9]
Sirica "Desmoplastic stroma and cholangiocarcinoma: clinical implications and therapeutic targeting" Hepatology (2014) 10.1002/hep.26762
[10]
Raggi "Impact of microenvironment and stem-like plasticity in cholangiocarcinoma: molecular networks and biological concepts" J Hepatol (2015) 10.1016/j.jhep.2014.09.007
[11]
Ren "Understanding tumor ecosystems by single-cell sequencing: promises and limitations" Genome Biol (2018) 10.1186/s13059-018-1593-z
[12]
Baslan "Unravelling biology and shifting paradigms in cancer with single-cell sequencing" Nat Rev Cancer (2017) 10.1038/nrc.2017.58
[13]
Levitin "Single-cell transcriptomic analysis of tumor heterogeneity" Trends Cancer (2018) 10.1016/j.trecan.2018.02.003
[14]
Yuan "Single-cell transcriptome analysis of lineage diversity in high-grade glioma" Genome Med (2018) 10.1186/s13073-018-0567-9
[15]
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

Anoop P. Patel, Itay Tirosh, John J. Trombetta et al.

Science 2014 10.1126/science.1254257
[16]
Savas "Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis" Nat Med (2018) 10.1038/s41591-018-0078-7
[17]
Lambrechts "Phenotype molding of stromal cells in the lung tumor microenvironment" Nat Med (2018) 10.1038/s41591-018-0096-5
[18]
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

Sidharth V. Puram, Itay Tirosh, Anuraag S. Parikh et al.

Cell 2017 10.1016/j.cell.2017.10.044
[19]
Peng "Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma" Cell Res (2019) 10.1038/s41422-019-0195-y
[20]
Zheng "Landscape of infiltrating T cells in liver cancer revealed by single-cell sequencing" Cell (2017) 10.1016/j.cell.2017.05.035
[21]
Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

Lichun Ma, Maria O. Hernandez, Yongmei Zhao et al.

Cancer Cell 2019 10.1016/j.ccell.2019.08.007
[22]
Zhang "Landscape and dynamics of single immune cells in hepatocellular carcinoma" Cell (2019) 10.1016/j.cell.2019.10.003
[23]
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Itay Tirosh, Benjamin Izar, Sanjay M. Prakadan et al.

Science 2016 10.1126/science.aad0501
[24]
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

Gabriela Bindea, Bernhard Mlecnik, Marie Tosolini et al.

Immunity 2013 10.1016/j.immuni.2013.10.003
[25]
Elyada "Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts" Cancer Discov (2019) 10.1158/2159-8290.cd-19-0094
[26]
Bartoschek "Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing" Nat Commun (2018) 10.1038/s41467-018-07582-3
[27]
Chen "Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling" Nat Commun (2014) 10.1038/ncomms4472
[28]
Garcia-Silva "Melanosomes foster a tumour niche by activating CAFs" Nat Cell Biol (2016) 10.1038/ncb3404
[29]
Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

Annette Becker, Basant Kumar Thakur, Joshua Mitchell Weiss et al.

Cancer Cell 2016 10.1016/j.ccell.2016.10.009
[30]
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Bruno Costa-Silva, Nicole M. Aiello, Allyson J. Ocean et al.

Nature Cell Biology 2015 10.1038/ncb3169
[31]
Su "CD10(+)GPR77(+) cancer-associated fibroblasts promote cancer formation and chemoresistance by sustaining cancer stemness" Cell (2018) 10.1016/j.cell.2018.01.009
[32]
Fang "Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer" Nat Commun (2018) 10.1038/s41467-017-02583-0
Cited By
505
Cholangiocarcinoma 2026: status quo, unmet needs and priorities

Jesús M. Banales, Pedro M. Rodrigues · 2025

Nature Reviews Gastroenterology &am...
Hepatic Stellate Cells Functional Heterogeneity in Liver Cancer

Laura Sererols-Viñas, Gemma Garcia-Vicién · 2025

Seminars in Liver Disease
Cancer-Associated Fibroblasts in Intrahepatic Cholangiocarcinoma

Silvia Affὸ, Laura Sererols-Viñas · 2025

The American Journal of Pathology
Frontiers in Cell and Developmental...
Friend or foe? The elusive role of hepatic stellate cells in liver cancer

Bruno Cogliati, Chittampalli N. Yashaswini · 2023

Nature Reviews Gastroenterology &am...
Nature Reviews Clinical Oncology
Cancer-associated fibroblasts in the single-cell era

Dor Lavie, Aviad Ben-Shmuel · 2022

Nature Cancer
Immunobiology of the biliary tract system

Niklas K. Björkström · 2022

Journal of Hepatology
Metrics
505
Citations
32
References
Details
Published
Nov 01, 2020
Vol/Issue
73(5)
Pages
1118-1130
License
View
Funding
National Natural Science Foundation of China Award: 81472341
National Key Research and Development Program of China Award: 2017YFA0103100
Beijing Municipal Commission of Education Award: KM201710005031
Cite This Article
Min Zhang, Hui Yang, Lingfei Wan, et al. (2020). Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma. Journal of Hepatology, 73(5), 1118-1130. https://doi.org/10.1016/j.jhep.2020.05.039
Related

You May Also Like

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

Peter R. Galle, Alejandro Forner · 2018

6,790 citations

Burden of liver diseases in the world

Sumeet K. Asrani, Harshad Devarbhavi · 2019

3,089 citations