miRNAs in Cancer (Review of Literature)

Beata Smolarz; Adam Durczyński; Hanna Romanowicz; Krzysztof Szyłło; Piotr Hogendorf

doi:10.3390/ijms23052805

journal article Open Access Mar 03, 2022

miRNAs in Cancer (Review of Literature)

Beata Smolarz

Adam Durczyński Hanna Romanowicz Krzysztof Szyłło Piotr Hogendorf

International Journal of Molecular Sciences Vol. 23 No. 5 pp. 2805 · MDPI AG

View at Publisher Save 10.3390/ijms23052805

Abstract

MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the course of processes of fundamental importance for the proper functioning of the organism. These processes include cell division, proliferation, differentiation, cell apoptosis and the formation of blood vessels. Altered expression of individual miRNAs has been shown in numerous cancers, which may indicate the oncogenic or suppressor potential of the molecules in question. This paper discusses the current knowledge about the possibility of using miRNA as a diagnostic marker and a potential target in modern anticancer therapies.

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Details

Published: Mar 03, 2022
Vol/Issue: 23(5)
Pages: 2805
License: View

Authors

B

Beata Smolarz

Laboratory of Cancer Genetics, Department of Pathology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland

A

Adam Durczyński

Department of General and Transplant Surgery, N. Barlicki Memorial Clinical Hospital, Medical University of Lodz, 90-001 Lodz, Poland

H

Hanna Romanowicz

Laboratory of Cancer Genetics, Department of Pathology, Polish Mother’s Memorial Hospital Research Institute, Rzgowska 281/289, 93-338 Lodz, Poland

K

Krzysztof Szyłło

Department of Gynaecology, Oncological Gynaecology and Endometriosis Treatment, Polish Mother’s Memorial Hospital Research Institute, Rzgowska-Lodz, 93-338 Lodz, Poland

P

Piotr Hogendorf

Department of General and Transplant Surgery, N. Barlicki Memorial Clinical Hospital, Medical University of Lodz, 90-001 Lodz, Poland

Cite This Article

Beata Smolarz, Adam Durczyński, Hanna Romanowicz, et al. (2022). miRNAs in Cancer (Review of Literature). International Journal of Molecular Sciences, 23(5), 2805. https://doi.org/10.3390/ijms23052805

miRNAs in Cancer (Review of Literature)

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